Understanding the complex rheology of human blood plasma

Blood plasma (BP) is a borderline non-Newtonian fluid. Few studies have characterized the rheology of BP and even less focused on understanding its subtle viscoelastic traits, which were only somewhat recently acknowledged. We use passive microrheology to measure bulk response human samples under shear at body ambient temperatures. Evidence subdiffusive behavior in mean-squared displacement observed highest frequencies probed, we attribute stress relaxation protein molecules or chains. Jeffreys-like complex moduli computed thereof. The microenvironments albumin, fibrinogen, gamma-globulin solutions (key proteins) probed as well. Single proteins an aqueous buffer showed no signs viscoelasticity within experimental resolution. Conversely, mixed together, they appear promote same kind short-term elastic seen plasma. All all, fresh look presented.